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In the near future, life-like androids with artificial intelligence have been created to help people with menial household tasks. The prototype, One, created by Roger Marshall and tested by his family, proves to be popular but flawed. Roger has been working on a new model, Two, whose improved features show promise of its super-human abilities. As tensions rise between Roger and...。米兰时装周期间，全球各地顶尖模特云集于此。闲暇时分，这群青春靓丽的女孩四处游玩，彻夜狂欢，尽享意大利的浪漫风情，却忽略了异国他乡潜在的危险。一个绰号“铅黄”的出租车骇客（Byron Deidra 饰）逡巡在夜店四周，专门猎取年轻漂亮的女孩。他将她们虏获，然后采取残酷的手段加以虐待。其手段残忍，且行踪诡异，始终是警方头疼的一大难题。 美国空姐琳达（Emmanuelle Seigner 饰）随机停留米兰，并准备和参加时装表演的妹妹萨琳娜（埃尔莎•帕塔奇 Elsa Pataky 饰）会面。姐妹尚未相聚，萨琳娜便突然失踪。从电话中听到异样的琳达求助警方，继而找到多年来一直追查“铅黄”的阿沃菲警官（阿德里安•布罗迪 Adrien Brody 饰）。一场猫鼠游戏慢慢展开……。